The Pleasanton Chamber of Commerce was organized in 1951 to fulfill the unmet needs of a growing and prospering community.

At that time it was named the "Pleasanton and North Pleasanton Chamber of Commerce", because the twin communities consolidated. As one report of the times stated: "Numerous instances were coming to the attention of the businessmen here of enterprises being lost through misunderstandings on the part of new people. New residents were sidetracked to other communities by unfair criticism of this community.